| 分子动力学模拟与分子生物力学 | |
| Alternative Title | Molecular Dynamics Simulation and Molecular Biomechanics |
吕守芹 ; 龙勉
| |
| Source Publication | 生物物理学报
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| 2012-01-31 | |
| Volume | 28Issue:1Pages:6-14 |
| ISSN | 1000-6737 |
| Abstract | 生物大分子的微观结构动力学决定其生物学功能,其力学-化学耦合规律是分子生物力学的重点关注方向。分子动力学模拟是耦合生物大分子力学-化学性质微观结构动力学基础的有效手段,其结果可用于预测结构-功能关系、指导实验设计和诠释实验结果。本文简要介绍了分子动力学模拟的方法学特点、基本工作原理及其在分子生物力学中的应用,并展望了未来可能的发展方向和应用前景。 |
| Other Abstract | Micro-structural dynamics of biomolecules governs their biological functions.Mechano-chemical coupling is a key issue in molecular biomechanics.Molecular dynamics simulation(MDS) is an effective approach to coordinate the biomolecular micro-structural dynamics with their mechanical and chemical features.The outcomes provide the bases in predicting the structure-function relationship,optimizing the experimental design,and interpreting the measured data.This mini-review briefly introduces the MDS approach,the... |
| Keyword | 分子动力学模拟 分子生物力学 微观结构动力学 结构-功能关系 |
| Subject Area | 生物力学 |
| URL | 查看原文 |
| Indexed By | CSCD |
| Language | 中文 |
| Funding Organization | 国家自然科学基金项目(30730032,11072251) |
| CSCD ID | CSCD:4435792 |
| Department | NML分子-细胞生物力学与空间生命科学 |
| Citation statistics |
Cited Times:4[CSCD]
[CSCD Record]
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| Document Type | 期刊论文 |
| Identifier | http://dspace.imech.ac.cn/handle/311007/46426 |
| Collection | 微重力重点实验室 |
| Corresponding Author | 龙勉 |
| Recommended Citation GB/T 7714 | 吕守芹,龙勉. 分子动力学模拟与分子生物力学[J]. 生物物理学报,2012,28,1,:6-14. |
| APA | 吕守芹,&龙勉.(2012).分子动力学模拟与分子生物力学.生物物理学报,28(1),6-14. |
| MLA | 吕守芹,et al."分子动力学模拟与分子生物力学".生物物理学报 28.1(2012):6-14. |
| Files in This Item: | Download All | |||||
| File Name/Size | DocType | Version | Access | License | ||
| C2012J-046.pdf（378KB） | 开放获取 | -- | View Download | |||
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