| Hydrodynamic cell enrichment in double spiral microfluidic channels | |
Sun JS ; Li MM; Liu C(刘超); Hu GQ(胡国庆); Jiang XY; Sun Jiashu
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| Source Publication | Chemical Sensors 10 -and- MEMS/NEMS 10 |
| 2012 | |
| Pages | 441-445 |
| Conference Name | Symposia on Chemical Sensors 10 - Chemical and Biological Sensors and Analytical Systems and Microfabricated and Nanofabricated Systems for MEMS/NEMS 10 - 222nd ECS Meeting/PRiME 2012 |
| Conference Date | OCT 07-12, 2012 |
| Conference Place | Honolulu, HI, United states |
| Abstract | Rapid cell separation and enrichment has attracted significant attention because of its important applications in cell biology studies and biomedical diagnostics. we have developed a compact microfluidic platform, composed of 6-loop double spiral microchannels, to separate cancer cells from blood cells. The curved geometry induces a Dean drag force acting on cells to compete with the inertial lift, resulting in different equilibrium positions for different sized cells. The separation chip is characterized with the mixture of 4T1 cells and the murine blood cells at different flow rates, with decent separation and enrichment efficiency. |
| WOS ID | WOS:000338266800056 |
| Department | LNM微纳米流体力学 |
| Funding Organization | MOST 2011CB933201 2009CB930001 2011CB707604 NSFC 51105086 21025520 90813032 CAS KJCX2-YW-M15 KJCX2YW-H18 |
| ISBN | 9781607683605 |
| URL | 查看原文 |
| Indexed By | CPCI-S ; EI |
| Language | 英语 |
| Citation statistics | |
| Document Type | 会议论文 |
| Identifier | http://dspace.imech.ac.cn/handle/311007/48288 |
| Collection | 非线性力学国家重点实验室 |
| Corresponding Author | Sun Jiashu |
| Recommended Citation GB/T 7714 | Sun JS,Li MM,Liu C,et al. Hydrodynamic cell enrichment in double spiral microfluidic channels[C]Chemical Sensors 10 -and- MEMS/NEMS 10,2012:441-445. |
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| File Name/Size | DocType | Version | Access | License | ||
| ECS Trans.-2013-Sun-（107KB） | 会议论文 | 开放获取 | CC BY-NC-SA | View Download | ||
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