| Application of supported phospholipids bilayer bilayers for biosensor based on imaging ellipsometry | |
Chen YY; Zhang YB; Wang CX ; Ding ZJ; Huang CH; Chang WR; Jin G(靳刚); Chang, W. R. ([email protected])
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| Source Publication | IFMBE Proceedings |
| 2009 | |
| Conference Name | World Congress on Medical Physics and Biomedical Engineering: Micro- and Nanosystems in Medicine, Active Implants, Biosensors |
| Conference Date | September 7, 2009 - September 12, 2009 |
| Conference Place | Munich, Germany |
| Abstract | Application of supported phospholipids bilayers (SPB) is presented for biosensor based on imaging ellipsometry. One SPB is prepared by covalent immobilization of phospholipids monolayer on silicon surface, and followed by adsorption of PEG functionalized phospholipids layer. Another is prepared by adsorption of the mixture of phospholipids and PEG functionalized phospholipids on the hydrophilic silicon surface. Results show that obvious resistance to non-specific protein adsorption on SPB is obtained, and proteins covalently immobilized on the bilayers by the terminal carboxyl group of PEG remain higher bioactivity than that immobilized on silicon surface directly. © 2009 Springer-Verlag. |
| Keyword | Bi-layer Carboxyl Groups Covalent Immobilization Functionalized Imaging Ellipsometry Microfiuidic Array Non-specific Protein Adsorption Phospholipids Bilayer Silicon Surfaces Supported Phospholipid Bilayers |
| ISBN | 9783642038860 |
| URL | 查看原文 |
| Indexed By | EI |
| Language | 英语 |
| Document Type | 会议论文 |
| Identifier | http://dspace.imech.ac.cn/handle/311007/60454 |
| Collection | 微重力重点实验室 |
| Corresponding Author | Chang, W. R. ([email protected]) |
| Recommended Citation GB/T 7714 | Chen YY,Zhang YB,Wang CX,et al. Application of supported phospholipids bilayer bilayers for biosensor based on imaging ellipsometry[C]IFMBE Proceedings,2009. |
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| File Name/Size | DocType | Version | Access | License | ||
| Ca2009-053.pdf（149KB） | 会议论文 | 开放获取 | CC BY-NC-SA | View Download | ||
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