| Force spectroscopy of single receptor-ligand bond using an optical trap | |
Zhang Y(章燕) ; Sun GY(孙淦云); Li N(李宁); Huo B(霍波); Lv SQ(吕守芹); Long M(龙勉); Zhang, Y.
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| Source Publication | 2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009 |
| 2009 | |
| Conference Name | 2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009 |
| Conference Date | November 2, 2009 - November 6, 2009 |
| Conference Place | Shanghai, China |
| Abstract | Here we developed an thermal fluctuation assay using optical trap technique, which enables to visualize consecutive binding-unbinding transition and to unravel the bond dissociation at low spring cosntant and low loading rate. This novel method provided further understandings in monitoring biophysics of receptor-ligand interactions. ©2009 Optical Society of America. |
| Keyword | Bond Dissociation Force Spectroscopy Low Loading Novel Methods Optical Trap Receptor-ligand Bonds Receptor-ligand Interactions Thermal Fluctuations Unbinding Transitions |
| ISBN | 9781557528773 |
| Indexed By | EI |
| Language | 英语 |
| Document Type | 会议论文 |
| Identifier | http://dspace.imech.ac.cn/handle/311007/60461 |
| Collection | 微重力重点实验室 |
| Corresponding Author | Zhang, Y. |
| Recommended Citation GB/T 7714 | Zhang Y,Sun GY,Li N,et al. Force spectroscopy of single receptor-ligand bond using an optical trap[C]2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009,2009. |
| Files in This Item: | Download All | |||||
| File Name/Size | DocType | Version | Access | License | ||
| Ca2009-060.pdf（2190KB） | 会议论文 | 开放获取 | CC BY-NC-SA | View Download | ||
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