| Quantitative Assessments of Mechanical Responses upon Radial Extracorporeal Shock Wave Therapy | |
Liu YJ; Chen XD(陈晓东) ; Guo AY; Liu SJ; Hu GQ(胡国庆)
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| Source Publication | ADVANCED SCIENCE
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| 2018-03-01 | |
| Volume | 5Issue:3Pages:1700797 |
| ISSN | 2198-3844 |
| Abstract | Although radial extracorporeal shock wave therapy (rESWT) has been widely used to treat orthopedic disorders with promising clinical results, rESWT largely relies on clinicians' personal experiences and arbitrary judgments, without knowing relationships between administration doses and effective doses at target sites. In fact, practitioners lack a general and reliable way to assess propagation and distribution of pressure waves inside biological tissues quantitatively. This study develops a methodology to combine experimental measurements and computational simulations to obtain pressure fields from rESWT through calibrating and validating computational models with experimental measurements. Wave pressures at the bottom of a petri dish and inside biological tissues are measured, respectively, by attaching and implanting flexible membrane sensors. Detailed wave dynamics are simulated through explicit finite element analyses. The data decipher that waves from rESWT radiate directionally and can be modeled as acoustic waves generated from a vibrating circular piston. Models are thus established to correlate pressure amplitudes at the bottom of petri dishes and in the axial direction of biological tissues. Additionally, a pilot simulation upon rESWT for human lumbar reveals a detailed and realistic pressure field mapping. This study will open a new avenue of personalized treatment planning and mechanism research for rESWT. |
| Keyword | experimental measurements explicit dynamics analysis extracorporeal shock wave therapy finite element models |
| DOI | 10.1002/advs.201700797 |
| URL | 查看原文 |
| Indexed By | SCI ; EI |
| Language | 英语 |
| WOS ID | WOS:000428310500022 |
| WOS Keyword | PLANTAR FASCIITIS ; ACOUSTIC FIELD ; DEVICE ; LITHOTRIPSY ; ULTRASOUND ; MODEL ; BONE ; INDENTATION ; EXPOSURE ; PULSES |
| WOS Research Area | Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary |
| WOS Subject | Chemistry ; Science & Technology - Other Topics ; Materials Science |
| Funding Organization | National Natural Science Foundation of China [11402274, 11772343] ; CAS Key Research Program of Frontier Sciences [QYZDB-SSW-JSC036] ; CAS Strategic Priority Research Program [XDB22040403] ; Beijing Science and Technology Plan [Z171100000417025] ; Beijing Nova Program Interdisciplinary Studies Cooperative Projects |
| Classification | 一类 |
| Ranking | 1 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://dspace.imech.ac.cn/handle/311007/77909 |
| Collection | 非线性力学国家重点实验室 |
| Affiliation | 1.Beijing Jishuitan Hosp, Orthoped Shock Wave Treatment Ctr, Spine Surg Dept, Beijing 100035, Peoples R China 2.Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China |
| Recommended Citation GB/T 7714 | Liu YJ,Chen XD,Guo AY,et al. Quantitative Assessments of Mechanical Responses upon Radial Extracorporeal Shock Wave Therapy[J]. ADVANCED SCIENCE,2018,5,3,:1700797. |
| APA | Liu YJ,陈晓东,Guo AY,Liu SJ,&胡国庆.(2018).Quantitative Assessments of Mechanical Responses upon Radial Extracorporeal Shock Wave Therapy.ADVANCED SCIENCE,5(3),1700797. |
| MLA | Liu YJ,et al."Quantitative Assessments of Mechanical Responses upon Radial Extracorporeal Shock Wave Therapy".ADVANCED SCIENCE 5.3(2018):1700797. |
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| File Name/Size | DocType | Version | Access | License | ||
| IrJ2018297.pdf（8610KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Download | |
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