IMECH-IR  > 微重力重点实验室
胚胎干细胞肝向分化过程对基底力学微环境的响应规律及机制
吕东媛; 罗春花; 郑璐; 张帆; 武亿; 龙勉
Source Publication医用生物力学
2021-08-15
Volume36Issue:S1Pages:156
Abstract目的人胚胎干细胞(hESC)能在体外分化为类肝细胞(HLC),可作为成体肝细胞的替代在重症肝病治疗和研究中发挥重要作用。hESC分化能力及终末分化细胞功能受周围物理力学因素调控,尤以微环境中硬度和拓扑耦合调控为甚。基于肝脏生理病理背景制备不同硬度耦合拓扑结构基底探讨其对hESC肝向分化的影响及机制。
Keyword胚胎干细胞 响应规律 微环境
Language中文
Funding Organization国家自然科学基金项目,31661143044,31627804,31870931
Ranking1
Document Type期刊论文
Identifierhttp://dspace.imech.ac.cn/handle/311007/88500
Collection微重力重点实验室
Affiliation1.中国科学院力学研究所
2.中国科学院大学工程科学学院
Recommended Citation
GB/T 7714
吕东媛,罗春花,郑璐,等. 胚胎干细胞肝向分化过程对基底力学微环境的响应规律及机制[J]. 医用生物力学,2021,36,S1,:156.
APA 吕东媛,罗春花,郑璐,张帆,武亿,&龙勉.(2021).胚胎干细胞肝向分化过程对基底力学微环境的响应规律及机制.医用生物力学,36(S1),156.
MLA 吕东媛,et al."胚胎干细胞肝向分化过程对基底力学微环境的响应规律及机制".医用生物力学 36.S1(2021):156.
Files in This Item: Download All
File Name/Size DocType Version Access License
Jp2021499.pdf(1929KB)期刊论文出版稿开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Lanfanshu
Similar articles in Lanfanshu
[吕东媛]'s Articles
[罗春花]'s Articles
[郑璐]'s Articles
Baidu academic
Similar articles in Baidu academic
[吕东媛]'s Articles
[罗春花]'s Articles
[郑璐]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[吕东媛]'s Articles
[罗春花]'s Articles
[郑璐]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Jp2021499.pdf
Format: Adobe PDF
This file does not support browsing at this time
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.