IMECH-IR  > 微重力重点实验室
力学微环境调控肝血窦内皮细胞表型维持与去分化
李宁; 李珮文; 张晓宇; 舒芯钰; 李旺; 吕守芹; 龙勉
Source Publication医用生物力学
2021-08-15
Volume36Issue:S1Pages:302
Abstract目的肝血窦内皮细胞(liver sinusoidal endothelial cells,LSEC)是肝内一种高度分化的非实质细胞,具有独特的表型特征,在肝脏组织稳态维持中起关键作用。基质硬度、血流剪切等力学微环境的变化是多种肝脏疾病发展过程中的重要因素,但其是否可以直接调控LSEC的表型维持或去分化尚不明确。方法体外培养小鼠原代LSEC细胞,
Keyword肝血窦内皮细胞 去分化 微环境
Language中文
Funding Organization国家自然科学基金项目,91642203,31627804,31870930
Ranking1
Document Type期刊论文
Identifierhttp://dspace.imech.ac.cn/handle/311007/88507
Collection微重力重点实验室
Affiliation1.中国科学院力学研究所
2.中国科学院大学工程科学学院
Recommended Citation
GB/T 7714
李宁,李珮文,张晓宇,等. 力学微环境调控肝血窦内皮细胞表型维持与去分化[J]. 医用生物力学,2021,36,S1,:302.
APA 李宁.,李珮文.,张晓宇.,舒芯钰.,李旺.,...&龙勉.(2021).力学微环境调控肝血窦内皮细胞表型维持与去分化.医用生物力学,36(S1),302.
MLA 李宁,et al."力学微环境调控肝血窦内皮细胞表型维持与去分化".医用生物力学 36.S1(2021):302.
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