| Stretchable Electronic Facial Masks for Skin Electroporation | |
Xu XK(徐新凯); Guo L(郭亮) ; Liu, Hao; Zhou ZX(周赞鑫); Li, Shuang; Gu, Qi; Ding, Shenglong; Guo, Haitao; Yan, Yan; Lan YQ(蓝昱群); Li QL(李沁蓝); Wei, Wanxin; Zhang, Jian; Liu C(刘崇); Su YW(苏业旺)
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| Corresponding Author | Su, Yewang([email protected]) |
| Source Publication | ADVANCED FUNCTIONAL MATERIALS
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| 2023-11-21 | |
| Pages | 14 |
| ISSN | 1616-301X |
| Abstract | A stretchable electronic facial mask (SEFM) for skin electroporation by transdermal drug delivery is introduced. The SEFM exhibits characteristics of reusability, water-resistant, low cost, and portability. To achieve these objectives while maintaining satisfactory mechanical and electrical performance of the device, two main areas are innovated: (1) Grinding and doping modification of conductive ink to enhance its adhesion to silicone and increase conductivity through material research, as well as mechanical structure design for stretching stability of conductive ink electrodes. (2) Doping modification of high-temperature vulcanizes silicone to address the issue of increased resistance during encapsulation due to the swell of conductive ink. The SEFM designed with these innovations, is validated in rat experiments, demonstrating a 3-4 times increase in drug intake compared to the control group without skin electroporation. Safety is confirmed, and the promotion of niacinamide drug delivery is verified in human volunteers. The materials-modified conductive ink and conductive silicone proposed in SEFM can be employed in other flexible wearable devices, and this platform has the potential for future integration of additional components to achieve expanded functionality and productization. A stretchable electronic facial mask (SEFM) for skin electroporation by transdermal drug delivery, enabling the delivery of drugs such as sodium hyaluronate (SH), aloe powder, beta-glucose, and d-panthenol. The SEFM significantly enhances drug intake, with a 3-4 times increase. This platform holds the potential for future integration of additional components to expand its functionality and facilitate product development.image |
| Keyword | conductive ink conductive silicone skin electroporation stretchable electronics |
| DOI | 10.1002/adfm.202311144 |
| Indexed By | SCI ; EI |
| Language | 英语 |
| WOS ID | WOS:001105679100001 |
| WOS Keyword | HUMAN STRATUM-CORNEUM ; HIGH-VOLTAGE ; TRANSPORT REGIONS ; ULTRASOUND ; MICRONEEDLES ; SILICONE |
| WOS Research Area | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| WOS Subject | Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter |
| Funding Project | Y.S. gratefully acknowledges support from the National Natural Science Foundation of China (grant 12172359), Key Research Program of Frontier Sciences of the Chinese Academy of Sciences (ZDBS-LY-JSC014), and CAS Interdisciplinary Innovation Team (JCTD-2020[12172359] ; National Natural Science Foundation of China[ZDBS-LY-JSC014] ; Key Research Program of Frontier Sciences of the Chinese Academy of Sciences[JCTD-2020-03] ; CAS Interdisciplinary Innovation Team |
| Funding Organization | Y.S. gratefully acknowledges support from the National Natural Science Foundation of China (grant 12172359), Key Research Program of Frontier Sciences of the Chinese Academy of Sciences (ZDBS-LY-JSC014), and CAS Interdisciplinary Innovation Team (JCTD-2020 ; National Natural Science Foundation of China ; Key Research Program of Frontier Sciences of the Chinese Academy of Sciences ; CAS Interdisciplinary Innovation Team |
| Classification | 一类 |
| Ranking | 1 |
| Contributor | Su, Yewang |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://dspace.imech.ac.cn/handle/311007/93494 |
| Collection | 非线性力学国家重点实验室 高温气体动力学国家重点实验室 流固耦合系统力学重点实验室 |
| Recommended Citation GB/T 7714 | Xu XK,Guo L,Liu, Hao,et al. Stretchable Electronic Facial Masks for Skin Electroporation[J]. ADVANCED FUNCTIONAL MATERIALS,2023:14.Rp_Au:Su, Yewang |
| APA | 徐新凯.,郭亮.,Liu, Hao.,周赞鑫.,Li, Shuang.,...&苏业旺.(2023).Stretchable Electronic Facial Masks for Skin Electroporation.ADVANCED FUNCTIONAL MATERIALS,14. |
| MLA | 徐新凯,et al."Stretchable Electronic Facial Masks for Skin Electroporation".ADVANCED FUNCTIONAL MATERIALS (2023):14. |
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| File Name/Size | DocType | Version | Access | License | ||
| Jp2023Fa004.pdf（6166KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Download | |
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