| A tough graphene nanosheet/hydroxyapatite composite with improved in vitro biocompatibility | |
Zhang L; Liu WW ; Yue CG; Zhang TH(张泰华); Li P; Xing ZW; Chen Y; Chen, Y (reprint author), Soochow Univ, Sch Mech & Elect Engn, Biomfg Res Ctr, 178 East Ganjiang Rd, Suzhou 215021, Peoples R China.
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| Source Publication | CARBON
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| 2013-09 | |
| Volume | 61Pages:105-115 |
| ISSN | 0008-6223 |
| Abstract | Mechanical properties and in vitro biocompatibility of graphene/hydroxyapatite (HA) composite synthesized using spark plasma sintering (SPS) are reported in this study. Raman spectroscopy corroborated that graphene nanosheets (GNSs) survived the harsh processing conditions of the selected SPS processing parameters. A 1.0 wt.% GNS/HA composite exhibits similar to 80% improvement in fracture toughness as compared to pure HA. GNS pull-out, grain bridging by GNS, crack bridging and crack deflection are the major toughening mechanisms that resist crack propagation. In vitro osteoblast growth tests illustrate that the added GNSs contribute to the improvement of both osteoblast adhesion and apatite mineralization. Therefore, the GNS/HA composite is expected to be a promising material for load-bearing orthopedic implants. (C) 2013 Elsevier Ltd. All rights reserved. |
| Keyword | Ha Coatings Hydroxyapatite Nanocomposites Mineralization Nanoindentation |
| Subject Area | 新型材料的力学问题 ; 实验固体力学 |
| URL | 查看原文 |
| Indexed By | SCI ; EI |
| Language | 英语 |
| WOS ID | WOS:000322208700011 |
| Funding Organization | National Natural Science Foundation of China [51275326, 11025212, 11272318]; Natural Science Foundation of Jiangsu Province of China [SBK2010212]; Opening fund of The State Key Laboratory of Nonlinear Mechanics |
| Department | LNM实验平台 |
| Classification | 一类 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://dspace.imech.ac.cn/handle/311007/47477 |
| Collection | 非线性力学国家重点实验室 |
| Corresponding Author | Chen, Y (reprint author), Soochow Univ, Sch Mech & Elect Engn, Biomfg Res Ctr, 178 East Ganjiang Rd, Suzhou 215021, Peoples R China. |
| Recommended Citation GB/T 7714 | Zhang L,Liu WW,Yue CG,et al. A tough graphene nanosheet/hydroxyapatite composite with improved in vitro biocompatibility[J]. CARBON,2013,61:105-115. |
| APA | Zhang L.,Liu WW.,Yue CG.,张泰华.,Li P.,...&Chen, Y .(2013).A tough graphene nanosheet/hydroxyapatite composite with improved in vitro biocompatibility.CARBON,61,105-115. |
| MLA | Zhang L,et al."A tough graphene nanosheet/hydroxyapatite composite with improved in vitro biocompatibility".CARBON 61(2013):105-115. |
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