| A generalized formula for inertial lift on a sphere in microchannels | |
Liu C ; Xue CD; Sun JS; Hu GQ(胡国庆); Hu, GQ (reprint author), Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China.
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| Source Publication | LAB ON A CHIP
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| 2016 | |
| Volume | 16Issue:5Pages:884-892 |
| ISSN | 1473-0197 |
| Abstract | Inertial microfluidics has been widely used in high-throughput manipulation of particles and cells by hydrodynamic forces, without the aid of externally applied fields. The performance of inertial microfluidic devices largely relies on precise prediction of particle trajectories that are determined by inertial lift acting on particles. The only way to accurately obtain lift forces is by direct numerical simulation (DNS); however, it is burdensome when applied to practical microchannels with complex geometries. Here, we propose a fitting formula for inertial lift on a sphere drawn from DNS data obtained in straight channels. The formula consists of four terms that represent the shear-gradient-induced lift, the wall-induced lift, the slip-shear lift, and the correction of the shear-gradient-induced lift, respectively. Notably, as a function of the parameters of a local flow field, it possesses good adaptability to complex channel geometries. This generalized formula is further implemented in the Lagrangian particle tracking method to realize fast prediction of particle trajectories in two types of widely used microchannels: a long serpentine and a double spiral microchannel, demonstrating its ability to efficiently design and optimize inertial microfluidic devices. |
| DOI | 10.1039/c5lc01522g |
| URL | 查看原文 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000371009700009 |
| WOS Keyword | LAGRANGIAN STATISTICS ; FLUID-MECHANICS ; MOTION ; DYNAMICS ; FIBERS ; MICROORGANISMS ; GRADIENT |
| WOS Research Area | Biochemistry & Molecular Biology ; Chemistry ; Science & Technology - Other Topics |
| WOS Subject | Biochemical Research Methods ; Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology |
| Funding Organization | We thank the National Natural Science Foundation of China (11572335, 11272321, and 91543125) for financial support. We sincerely thank Dr. William D. Henshaw for making the finite-difference code - Overture available to us. The numerical simulations were performed on TianHe-1(A) at the National Supercomputing Center in Tianjin. |
| Department | LNM微纳米流体力学 |
| Classification | 一类 |
| Ranking | True |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://dspace.imech.ac.cn/handle/311007/58663 |
| Collection | 非线性力学国家重点实验室 |
| Corresponding Author | Hu, GQ (reprint author), Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China. |
| Recommended Citation GB/T 7714 | Liu C,Xue CD,Sun JS,et al. A generalized formula for inertial lift on a sphere in microchannels[J]. LAB ON A CHIP,2016,16,5,:884-892. |
| APA | Liu C,Xue CD,Sun JS,Hu GQ,&Hu, GQ .(2016).A generalized formula for inertial lift on a sphere in microchannels.LAB ON A CHIP,16(5),884-892. |
| MLA | Liu C,et al."A generalized formula for inertial lift on a sphere in microchannels".LAB ON A CHIP 16.5(2016):884-892. |
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| a2016-118.pdf（443KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Download | |
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