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基于(类)器官芯片研究肝脏疾病的力学调控机制
期刊论文
医用生物力学, 2024, 卷号: 39, 期号: S1, 页码: 285./通讯作者:龙勉
Authors:
杜宇
;
李旺
;
李宁
;
龙勉
Adobe PDF(1303Kb)
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Submit date:2024/10/18
器官芯片
组织界面
肝脏疾病
类器官
FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration
期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17./通讯作者:Li, Ning, Long, Mian
Authors:
Zhang XY(张晓宇)
;
Li PW(李培文)
;
Zhou J(周瑾)
;
Zhang ZL(张子良)
;
Wu H(吴欢)
;
Shu XY(舒芯钰)
;
Li W(李旺)
;
Wu Y(武亿)
;
Du Y(杜宇)
;
Lv DY(吕东媛)
;
Lv SQ(吕守芹)
;
Li N(李宁)
;
Long M(龙勉)
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Submit date:2024/04/02
Liver sinusoidal endothelial cells
Fenestrae
Liver fibrosis
Cytoskeleton remodeling
FAK
MAPK
Direct mechanical exposure initiates hepatocyte proliferation
期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13./通讯作者:Li, Ning, Long, Mian
Authors:
Li, Wang
;
Wu Y(武亿)
;
Hu, Wenhui
;
Zhou J(周瑾)
;
Shu XY(舒芯钰)
;
Zhang XY(张晓宇)
;
Zhang, Ziliang
;
Wu, Huan
;
Du, Yu
;
Lv DY(吕东媛)
;
Lv SQ(吕守芹)
;
Li N(李宁)
;
Long M(龙勉)
Adobe PDF(3334Kb)
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Submit date:2024/01/02
Mechanotransduction
FAK
hepatic sinusoid chip
力学拉伸促进肝血窦内皮细胞再生因子分泌和肝细胞增殖
会议论文
中国力学学会第四届全国力学博士生学术论坛, 合肥, 2023-11-18-20
Authors:
武亿
;
李林达
;
李旺
;
李宁
;
吕东媛*龙勉.
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Submit date:2024/06/04
DNA methyltransferase 1 deficiency improves macrophage motility and wound healing by ameliorating cholesterol accumulation
期刊论文
NPJ REGENERATIVE MEDICINE, 2023, 卷号: 8, 期号: 1, 页码: 29./通讯作者:Yao, WJ, Zhou, J (corresponding author), Peking Univ, Sch Basic Med Sci, Dept Physiol & Pathophysiol, Beijing 100191, Peoples R China., Zhou, J (corresponding author), Peking Univ, State Key Lab Vasc Homeostasis & Remodeling, Beijing 100191, Peoples R China., Zhou, J (corresponding author), Peking Univ, Natl Hlth Commiss Key Lab Cardiovasc Mol Biol & Re, Beijing Key Lab Cardiovasc Receptors Res, Beijing 100191, Peoples R China.
Authors:
Zhao, Chuanrong
;
Yang, Qianru
;
Tang, Runze
;
Li, Wang
;
Wang, Jin
;
Yang, Fangfang
;
Zhao, Jianan
;
Zhu, Juanjuan
;
Pang, Wei
;
Li N(李宁)
;
Zhang, Xu
;
Tian, Xiao Yu
;
Yao, Weijuan
;
Zhou, Jing
Adobe PDF(4818Kb)
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Submit date:2023/07/17
剪切应力及基质硬度调控肝细胞功能的生物力学机制
学位论文
博士论文,北京: 中国科学院大学, 2023
Authors:
李旺
Adobe PDF(8757Kb)
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Submit date:2023/06/26
剪切应力
基质硬度
增殖
肝细胞特异性功能
力学转导
Biomechanics in liver regeneration after partial hepatectomy
期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2023, 卷号: 11, 页码: 1165651./通讯作者:Lu, DY, Long, M (corresponding author), Chinese Acad Sci, Ctr Biomech & Bioengn, Beijing Key Lab Engn Construct & Mechanobiol, Beijing, Peoples R China., Lu, DY, Long, M (corresponding author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Nat Micrograv Lab, Beijing, Peoples R China., Lu, DY, Long, M (corresponding author), Univ Chinese Acad Sci, Sch Engn Sci, Beijing, Peoples R China.
Authors:
Wu Y(武亿)
;
Li N(李宁)
;
Shu XY(舒芯钰)
;
Li W(李旺)
;
Zhang XY(张晓宇)
;
Lv DY(吕东媛)
;
Long M(龙勉)
Adobe PDF(2065Kb)
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Submit date:2023/07/17
liver regeneration
partial hepatectomy
hemodynamics
mechanical loading
mechanotransduction
Potential Roles of YAP/TAZ Mechanotransduction in Spaceflight-Induced Liver Dysfunction
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 3, 页码: 20./通讯作者:李宁,龙勉
Authors:
Li W(李旺)
;
Shu XY(舒芯钰)
;
Zhang XY(张晓宇)
;
Zhang ZL(张子良)
;
Sun SJ(孙树津)
;
Li N(李宁)
;
Long M(龙勉)
Adobe PDF(1498Kb)
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Submit date:2023/03/20
microgravity
liver metabolism
mechanosensing
cytoskeleton
nuclear deformation
phase separation
Trail Formation Alleviates Excessive Adhesion and Maintains Efficient Neutrophil Migration
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2023./通讯作者:Zhang, Y, Long, M (corresponding author), Chinese Acad Sci, Ctr Biomech & Bioengn, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100190, Peoples R China., Zhang, Y, Long, M (corresponding author), Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construction & Mechanobiol, Beijing 100190, Peoples R China., Zhang, Y, Long, M (corresponding author), Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China.
Authors:
Hu WH(胡文慧)
;
Gao WB(高文博)
;
Gong YX(龚一心)
;
Guo P(郭盼)
;
Li W(李旺)
;
Shu XY(舒芯钰)
;
Lv SQ(吕守芹)
;
Zeng, Zhu
;
Zhang Y(章燕)
;
Long M(龙勉)
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Submit date:2023/04/20
neutrophil migration
trail release
rear contraction
fi2 integrin
cell adhesion
Towards a predictive kinetic model of 3-ethyltoluene: Evidence concerning fuel-specific intermediates in the flow reactor pyrolysis with insights into model implications
期刊论文
PROCEEDINGS OF THE COMBUSTION INSTITUTE, 2023, 卷号: 39, 期号: 1, 页码: 179-188./通讯作者:Wang, J (corresponding author), Beihang Univ, Sch Energy & Power Engn, Natl Key Lab Sci & Technol Aeroengine Aerothermody, Beijing 100191, Peoples R China., Yang, JZ (corresponding author), Univ Sci & Technol China, Natl Synchrotron Radiat Lab, Hefei 230029, Anhui, Peoples R China.
Authors:
Wang, Qianpeng
;
Yang, Mo
;
Wang, Juan
;
Yang, Jiuzhong
;
Zhao, Long
;
Li, Wang
;
Wang, Changyang
;
Lu, Tenglong
;
Li YJ(李昱君)
Adobe PDF(2132Kb)
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Submit date:2023/07/17
3-Ethyltoluene
High temperature pyrolysis
Aromatics
Kinetic modeling
Methylbenzyl radical