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基于肝再生芯片解析肝系细胞功能的力学调控机制 学位论文
博士论文，北京: 中国科学院大学, 2024
Authors:  舒芯钰
Adobe PDF(8907Kb)  |  Favorite  |  View/Download：1052/2  |  Submit date：2025/01/21
肝再生芯片  机械拉伸  流体剪切  肝血窦内皮细胞  肝细胞  
Stretch-induced hepatic endothelial mechanocrine promotes hepatocyte proliferation 期刊论文
HEPATOLOGY, 2024./通讯作者：Lü DY, Long M
Authors:  Wu Y(武亿);  Li LD(李林达);  Li, Wang;  Li N(李宁);  Zhang XY(张晓宇);  Zheng L(郑璐);  Zhong SY(钟绍宇);  Lv SQ(吕守芹);  Shu XY(舒芯钰);  Zhou J(周瑾);  Ai, Ding;  Gao, Ming;  Liu, Sijin;  Lv DY(吕东媛);  Long M(龙勉)
Favorite  |  View/Download：33/0  |  Submit date：2024/12/02
HB-EGF  liver regeneration  liver sinusoidal endothelial cell  mechanotransduction  mechanical stretch  
基于肝脏器官芯片研究拉伸与剪切协同调控肝脏再生的机制 期刊论文
医用生物力学, 2024, 卷号: 39, 期号: S1, 页码: 255./通讯作者：杜宇, 龙勉
Authors:  舒芯钰;  李宁;  宋超洋;  杜宇;  龙勉
Adobe PDF(1304Kb)  |  Favorite  |  View/Download：67/40  |  Submit date：2024/10/18
肝脏再生  微环境  肝血窦内皮细胞  器官芯片  肝再生  协同调控  
Deciphering the role of mechanical forces in liver regeneration by a biomimetic liver regeneration chip 期刊论文
JOURNAL OF HEPATOLOGY, 2024, 卷号: 80, 页码: S83-S84
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Du Y(杜宇);  Long M(龙勉)
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FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17./通讯作者：Li, Ning, Long, Mian
Authors:  Zhang XY(张晓宇);  Li PW(李培文);  Zhou J(周瑾);  Zhang ZL(张子良);  Wu H(吴欢);  Shu XY(舒芯钰);  Li W(李旺);  Wu Y(武亿);  Du Y(杜宇);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Favorite  |  View/Download：99/0  |  Submit date：2024/04/02
Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK  
Direct mechanical exposure initiates hepatocyte proliferation 期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13./通讯作者：Li, Ning, Long, Mian
Authors:  Li, Wang;  Wu Y(武亿);  Hu, Wenhui;  Zhou J(周瑾);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang, Ziliang;  Wu, Huan;  Du, Yu;  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
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Mechanotransduction  FAK  hepatic sinusoid chip  
A Biomimetic Liver Regeneration Chip for Studying Synergistic Effects of Mechanical Stretch and Shear Stress 会议论文
第二十次中国暨国际生物物理大会, 长沙, 2023年7月19日-23日
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Du Y(杜宇);  Long M(龙勉)
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Biomechanics in liver regeneration after partial hepatectomy 期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2023, 卷号: 11, 页码: 1165651./通讯作者：Lu, DY, Long, M (corresponding author), Chinese Acad Sci, Ctr Biomech & Bioengn, Beijing Key Lab Engn Construct & Mechanobiol, Beijing, Peoples R China., Lu, DY, Long, M (corresponding author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Nat Micrograv Lab, Beijing, Peoples R China., Lu, DY, Long, M (corresponding author), Univ Chinese Acad Sci, Sch Engn Sci, Beijing, Peoples R China.
Authors:  Wu Y(武亿);  Li N(李宁);  Shu XY(舒芯钰);  Li W(李旺);  Zhang XY(张晓宇);  Lv DY(吕东媛);  Long M(龙勉)
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liver regeneration  partial hepatectomy  hemodynamics  mechanical loading  mechanotransduction  
Coupling of Shear Stress and Stretch in a Biomimetic Liver Regeneration Chip (LRC) 会议论文
2023年中国生物医学工程大会暨创新医疗峰会, 苏州, 2023年5月18日-21日
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Du Y(杜宇);  Long M(龙勉)
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Potential Roles of YAP/TAZ Mechanotransduction in Spaceflight-Induced Liver Dysfunction 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 3, 页码: 20./通讯作者：李宁，龙勉
Authors:  Li W(李旺);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang ZL(张子良);  Sun SJ(孙树津);  Li N(李宁);  Long M(龙勉)
Adobe PDF(1498Kb)  |  Favorite  |  View/Download：190/30  |  Submit date：2023/03/20
microgravity  liver metabolism  mechanosensing  cytoskeleton  nuclear deformation  phase separation