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Gravity-Vector Induces Mechanical Remodeling of rMSCs via Combined Substrate Stiffness and Orientation 期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 卷号: 9, 页码: 14./通讯作者：Long, Mian
Authors:  Zhang C(张晨);  Lv DY(吕东媛);  Zhang F(张帆);  Wu Y(武亿);  Zheng L(郑鲁);  Zhang XY(张晓宇);  Li Z(李展);  Sun SJ(孙树津);  龙勉Mian
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substrate stiffness  orientation  mechanosensing  nucleus translocation  cytoskeletal remodeling  focal adhesion complex reorganization  cellular morphology  
Hepatic differentiation of human embryonic stem cells by coupling substrate stiffness and microtopography 期刊论文
BIOMATERIALS SCIENCE, 2021, 页码: 15./通讯作者：Long, Mian
Authors:  Luo CH(罗春花);  Lv DY(吕东媛);  Zheng L(郑鲁);  Zhang F(张帆);  Zhang X(张潇);  Lv SQ(吕守芹);  Zhang C(张晨);  Jia Xiaohua;  Shu XY(舒芯钰);  Li PW(李培文);  Li Z(李展);  Long M(龙勉)
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Mechanical remodeling of normally sized mammalian cells under a gravity vector 期刊论文
FASEB JOURNAL, 2017, 卷号: 31, 期号: 2, 页码: 802-813
Authors:  Zhang C;  Zhou LW(周吕文);  Zhang F(张帆);  Lv DY(吕东媛);  Li N(李宁);  Zheng L;  Xu YH(徐艳红);  Li Z;  Sun SJ(孙树津);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
View  |  Adobe PDF(3686Kb)  |  Favorite  |  View/Download：601/205  |  Submit date：2017/07/24
Gravity-directed  Mechanosensing  Nucleus Translocation  Cytoskeletal Remodeling  Fac Reorganization  
Experimental Investigation of Dynamic Fracture Behaviors of Polymethyl Methacrylate 会议论文
23rd World Forum on Advanced Polymeric Materials (POLYCHAR), Univ Nebraska Lincoln, Lincoln, NE, MAY 11-15, 2015
Authors:  Gao GY;  Zhou J;  Li Z;  Li, Z (reprint author), Peking Univ, State Key Lab Turbulence & Complex Syst, Beijing 100871, Peoples R China.;  Li, Z (reprint author), Peking Univ, Coll Engn, Beijing 100871, Peoples R China.
View  |  Adobe PDF(2033Kb)  |  Favorite  |  View/Download：353/162  |  Submit date：2017/05/12
Crack Interaction  Fracture  Optical Method Of Caustics  Semi-circular Bending  Toughness  Stress Intensity Factor  Semicircular Bend Technique  Crack-propagation  Brittle-fracture  Caustic Analysis  Specimen  Pmma  Parallel  Field  Rock  
A case study integrating numerical simulation and GB-InSAR monitoring to analyze flexural toppling of an anti-dip slope in Fushun open pit 期刊论文
ENGINEERING GEOLOGY, 2015, 卷号: 197, 页码: 20-32
Authors:  Li Z;  Wang JA;  Li L;  Wang LX(王理想);  Liang RY;  Liang, RY (reprint author), Univ Akron, Dept Civil Engn, Akron, OH 44325 USA.
View  |  Adobe PDF(2891Kb)  |  Favorite  |  View/Download：533/207  |  Submit date：2016/01/08
Flexural Toppling  Anti-dip Slope  Numerical Modeling  Cdem  Gb-insar  Monitoring  
基底力学微环境对干细胞生物学功能的影响 会议论文
第十一届全国生物力学学术会议暨第十三届全国生物流变学学术会议会议, 中国山西太原, 2015-10-10
Authors:  吕东媛;  罗春花;  张晨;  李展;  宫元卫;  张帆;  孙树津;  龙勉
View  |  Adobe PDF(184Kb)  |  Favorite  |  View/Download：566/166  |  Submit date：2016/08/16
微环境  三维尺寸  拓扑结构  模拟体  多潜能细胞  Niche  干性  定向分化能力  细胞生物学特性  细胞生长  
Differential regulation of morphology and stemness of mouse embryonic stem cells by substrate stiffness and topography 期刊论文
BIOMATERIALS, 2014, 卷号: 35, 期号: 13, 页码: 3945-3955
Authors:  Lv DY(吕东媛);  Luo CH;  Zhang C;  Li Z;  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, Beijing 100190, Peoples R China.
View  |  Adobe PDF(3274Kb)  |  Favorite  |  View/Download：1404/445  |  Submit date：2014/06/05
Stiffness  Topography  Stem Cell  Sternness  Morphology  
Differential regulation of stiffness, topography, and dimension of substrates in rat mesenchymal stem cells 期刊论文
BIOMATERIALS, 2013, 卷号: 34, 期号: 31, 页码: 7616-7625
Authors:  Li Z(李展);  Gong YW(宫元卫);  Sun SJ(孙树津);  Du Y(杜宇);  Lv DY(吕东媛);  Liu XF(刘晓锋);  Long M(龙勉);  Sun, SJ (reprint author), Chinese Acad Sci, Ctr Biomech & Bioengn, Beijing 100190, Peoples R China.
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Stiffness  Topography  Dimension  Stem Cell  Proliferation  Differentiation  
一种用于悬浮细胞微重力效应模拟的培养系统 专利
发明授权.一种用于悬浮细胞微重力效应模拟的培养系统, 授权公告号: CN102329729B, 申请日期: 2011-10-08, 授权公告日期: 2013-05-29
Inventors:  龙勉;  孙树津;  高宇欣;  李展;  陈娟
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基底微拓扑结构对细胞生物学行为的影响 期刊论文
医用生物力学, 2013, 卷号: 28, 期号: 1, 页码: 115-120
Authors:  宫元卫;  孙树津;  吕东媛;  李展;  龙勉
Adobe PDF(477Kb)  |  Favorite  |  View/Download：1629/503  |  Submit date：2013/04/07
基底微拓扑结构  细胞增殖  干细胞分化  细胞骨架