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Rotating culture regulates the formation of HepaRG-derived liver organoids via YAP translocation 期刊论文
BMC BIOLOGY, 2024, 卷号: 22, 期号: 1, 页码: 262./通讯作者：Lue DY, Long M
Authors:  Zhong SY(钟绍宇);  Zheng L(郑璐);  Wu Y(武亿);  Sun SJ(孙树津);  Luo, Qing;  Song, Guanbin;  Lv DY(吕东媛);  Long M(龙勉)
Favorite  |  View/Download：8/0  |  Submit date：2024/12/02
Liver organoids  HepaRG cells  Rotating Flat Chamber  Rotating culture  YAP  Mechanotransduction  
Stretch-induced hepatic endothelial mechanocrine promotes hepatocyte proliferation 期刊论文
HEPATOLOGY, 2024./通讯作者：Lü DY, Long M
Authors:  Wu Y(武亿);  Li LD(李林达);  Li, Wang;  Li N(李宁);  Zhang XY(张晓宇);  Zheng L(郑璐);  Zhong SY(钟绍宇);  Lv SQ(吕守芹);  Shu XY(舒芯钰);  Zhou J(周瑾);  Ai, Ding;  Gao, Ming;  Liu, Sijin;  Lv DY(吕东媛);  Long M(龙勉)
Favorite  |  View/Download：10/0  |  Submit date：2024/12/02
HB-EGF  liver regeneration  liver sinusoidal endothelial cell  mechanotransduction  mechanical stretch  
Direct mechanical exposure initiates hepatocyte proliferation 期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13./通讯作者：Li, Ning, Long, Mian
Authors:  Li, Wang;  Wu Y(武亿);  Hu, Wenhui;  Zhou J(周瑾);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang, Ziliang;  Wu, Huan;  Du, Yu;  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Adobe PDF(3334Kb)  |  Favorite  |  View/Download：117/19  |  Submit date：2024/01/02
Mechanotransduction  FAK  hepatic sinusoid chip  
Biomechanics in liver regeneration after partial hepatectomy 期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2023, 卷号: 11, 页码: 1165651./通讯作者：Lu, DY, Long, M (corresponding author), Chinese Acad Sci, Ctr Biomech & Bioengn, Beijing Key Lab Engn Construct & Mechanobiol, Beijing, Peoples R China., Lu, DY, Long, M (corresponding author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Nat Micrograv Lab, Beijing, Peoples R China., Lu, DY, Long, M (corresponding author), Univ Chinese Acad Sci, Sch Engn Sci, Beijing, Peoples R China.
Authors:  Wu Y(武亿);  Li N(李宁);  Shu XY(舒芯钰);  Li W(李旺);  Zhang XY(张晓宇);  Lv DY(吕东媛);  Long M(龙勉)
Adobe PDF(2065Kb)  |  Favorite  |  View/Download：133/15  |  Submit date：2023/07/17
liver regeneration  partial hepatectomy  hemodynamics  mechanical loading  mechanotransduction  
Receptor-Ligand Binding: Effect of Mechanical Factors 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 10, 页码: 9062./通讯作者：Ji, J
Authors:  Du, Ruotian;  Li L(李龙);  Ji, Jing;  Fan, Yubo
Adobe PDF(2331Kb)  |  Favorite  |  View/Download：53/7  |  Submit date：2023/06/15
receptor-ligand binding  tension  shear stress  stretch  compression  substrate stiffness  biomechanics  mechanotransduction  
Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis 期刊论文
BIOACTIVE MATERIALS, 2022, 卷号: 17, 页码: 406-424./通讯作者：Zhou, Jing
Authors:  Wang, Jin;  Xie, Si-an;  Li N(李宁);  Zhang, Tao;  Yao, Weijuan;  Zhao, Hucheng;  Pang, Wei;  Han, Lili;  Liu, Jiayu;  Zhou, Jing
Adobe PDF(21819Kb)  |  Favorite  |  View/Download：392/50  |  Submit date：2022/06/10
Matrix stiffness  Inflammation  DDR1  DNMT1  Mechanotransduction  
Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer 期刊论文
ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448./通讯作者：Long, M (corresponding author), Chinese Acad Sci, Inst Mech, Beijing 100190, Peoples R China.
Authors:  Li N(李宁);  Zhang XY(张晓宇);  Zhou J(周瑾);  Li W(李旺);  Shu XY(舒芯钰);  Wu Y(武亿);  Long M(龙勉)
Adobe PDF(2553Kb)  |  Favorite  |  View/Download：430/132  |  Submit date：2022/10/23
Liver tissue stiffness  Shear stress  Hydrostatic pressure  Hepatocytes  Hepatocellular carcinoma  Liver sinusoidal endothelial cells  Hepatic stellate cells  Mechanotransduction pathways  Mechanomedicine  Drug design and delivery  
Mechanical strength determines Ca2+ transients triggered by the engagement of beta(2) integrins to their ligands 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 387, 期号: 2, 页码: 7./通讯作者：Long, Mian
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Huang DD(黄丹丹);  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(1108Kb)  |  Favorite  |  View/Download：567/210  |  Submit date：2020/04/07
beta(2) integrin  Ligands  Calcium transients  Bond strength  Mechanotransduction  Shear stress  
Microgravity-induced hepatogenic differentiation of rBMSCs on board the SJ-10 satellite 期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 3, 页码: 4273-4286./通讯作者：Long, M
Authors:  Lv DY(吕东媛);  Sun SJ(孙树津);  Zhang F(张帆);  Luo CH(罗春花);  Zheng L;  Wu Y(武毅);  Li N(李宁);  Zhang C;  Wang CZ;  Chen Q;  Long M(龙勉)
View  |  Adobe PDF(3477Kb)  |  Favorite  |  View/Download：352/111  |  Submit date：2019/04/11
mesenchymal stem cells  mechanotransduction  hepatocyte  signaling pathway  
Microgravity-Induced Alterations of Inflammation-Related Mechanotransduction in Endothelial Cells on Board SJ-10 Satellite 期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9, 页码: 1025
Authors:  Li N(李宁);  Wang CZ(王成之);  Sun SJ(孙树津);  Zhang C(张晨);  Lv DY(吕东媛);  Chen Q(陈琴);  Long M(龙勉)
View  |  Adobe PDF(3456Kb)  |  Favorite  |  View/Download：653/435  |  Submit date：2018/10/19
Microgravity  Sj-10 Satellite  Endothelial Cells  Adhesive Molecules  Cytoskeleton  Mechanotransduction  Nitric Oxide  Exosome Rna